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080201A Organ pathology I, 9.5 ECTS cr 
Code 080201A  Validity 01.01.1950 -
Name Organ pathology I  Abbreviation Organ pathology 
Scope9.5 ECTS cr   
Type Intermediate Studies Discipline5401 Medicine 
  Grading1 - 5, pass, fail 
Preceding studies
    040108A General Pathology
Unit Medicine 

Karttunen, Tuomo Juhani 

ECTS Credits 

13 ECTS Credits



Learning outcomes 

This course focuses on the essential features of etiology, pathogenesis and structural changes of diseases of the different organ systems. Pathophysiological aspects of diseases are reviewed as well as relationship between the abnormal function and structure and the clinical manifestations of disease, such as symptoms and clinical findings. Session on cell and molecular biology of cancer deals with pathogenesis of malignant neoplasms and the utilization of molecular biological techniques in the evaluation of neoplasms.

After the course, students should be able to describe etiology and pathogenesis of the most important diseases of each organ system, and the structural abnormalities of such diseases. The student should be able to explain how structural and functional abnormalities manifest themselves as clinical symptoms and signs. In addition, students should be able to identify and classify the most common types of macroscopic and microscopic abnormalities in different organ systems. He/she should know the most important sources of error in surgical pathological and cytological diagnostics, and be prepared on a proper teamwork with pathologists in his/her clinical work, for the best of his/her patients.



Methods of pathology. Sources of errors in surgical pathology and diagnostic cytology. Pathology of systemic diseases. Pathology of the circulatory system. Pathology of the liver, biliary tract and pancreas. Pathology of the oral tissues, salivary gland and the gastrointestinal tract. Pathology of the respiratory tract and the lungs. Hematopathology including pathology of the lymph nodes and the spleen. Oto-, rhino- and laryngolocical pathology. Ophthalmic pathology. Pathology of the kidney, urinary tract and male genitals. Pathology of the soft tissue, bone, joints and tendons. Endocrine pathology. Neuropathology. Pathology of the muscular system. Breast pathology. Cellular and molecular biology of cancer. 


Learning activities and teaching methods 

Lectures 48 h, theme days 12 h, practical training 33 h, exam 3 t


Recommended or required reading 

Text books: Underwood JCE: General and Systematic Pathology, 2009 or 2004 (organ pathology section) or: Kumar V et al.: Basic Pathology, 2007 tai 2003. Alternative text books : Cotran et al.: Pathologic basis of disease 2010 or 2004 ; Rubin & Farber: Pathology, 2005 or 1999). Manuals for the practical trainings (in Finnish), available in electronic form in Optima: Mikroskooppiharjoitusten opas (A guide for microscopy practicals), Obduktiotekniikan opas (A guide for autopsy technique). Lecture notes (mostly in Finnish).


Assessment methods and criteria 

Participation in the practicals, theme days and passing the final exam.



0-5. Final grade in Organ pathology (0-5) will be calculated on the basis of grades in Organ pathology part I and Organ pathology part II, both affecting the grade in proportion of the amount of credits of both of these courses. 


Person responsible 

Professor Tuomo Karttunen



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